Vaccinations

Vaccination Reference Library

Comprehensive guide to adult and pediatric immunizations

Influenza (Flu)

Schedule

Annual (everyone >6 months)

Indications

Prevention of seasonal influenza

Contraindications

Severe allergic reaction to previous dose

Notes

Live attenuated (nasal) contraindicated in pregnancy and immunocompromised.

Tdap (Tetanus, Diphtheria, Pertussis)

Schedule

Every 10 years (Td or Tdap), 1 dose Tdap for all adults

Indications

Tetanus prophylaxis, wound management, pregnancy (27-36 weeks)

Contraindications

Encephalopathy within 7 days of previous pertussis vaccine

Notes

Tdap recommended for every pregnancy.

MMR (Measles, Mumps, Rubella)

Schedule

2 doses (Childhood)

Indications

Immunity against measles, mumps, rubella

Contraindications

Pregnancy, Severe immunodeficiency (Live vaccine)

Notes

Adults without evidence of immunity should get at least 1 dose.

Varicella (Chickenpox)

Schedule

2 doses

Indications

Immunity against varicella

Contraindications

Pregnancy, Severe immunodeficiency (Live vaccine)

Notes

Check titers if history uncertain.

Zoster (Shingrix)

Schedule

2 doses separated by 2-6 months

Indications

Adults ≥50 years (regardless of chickenpox history)

Contraindications

Current herpes zoster infection

Notes

Recombinant vaccine, preferred over live Zostavax.

Pneumococcal (PCV20 or PCV15+PPSV23)

Schedule

Single dose PCV20 OR PCV15 followed by PPSV23

Indications

Adults ≥65, or 19-64 with risk factors

Contraindications

Severe allergic reaction

Notes

Risk factors: Chronic heart/lung/liver/renal disease, diabetes, smoking.

COVID-19

Schedule

Primary series + Boosters as per current CDC guidelines

Indications

Prevention of COVID-19

Contraindications

Severe allergic reaction to component

Notes

Keep updated with latest variant boosters.

Hepatitis B

Schedule

2 or 3 dose series depending on brand

Indications

All adults 19-59, ≥60 with risk factors

Contraindications

Hypersensitivity to yeast

Notes

Check titers for healthcare workers.

Hepatitis A

Schedule

2 doses separated by 6-18 months

Indications

Travel, chronic liver disease, MSM, HBV co-infection

Contraindications

Severe allergic reaction

Notes

Rapid schedule available (0, 7, 21-30 days) for urgent travel.

HPV (Gardasil 9)

Schedule

3 doses (0, 1-2, 6 months) if age 15+; 2 doses if <15

Indications

Ages 11-26 (standard), up to 45 for catch-up

Contraindications

Severe allergic reaction to vaccine components

Notes

9-valent covers most carcinogenic strains. Can prevent cervical, anal, oropharyngeal cancers.

Meningococcal (MenACWY & MenB)

Schedule

MenACWY: 2 doses (0, 1 yr) or 1 dose; MenB: 2 doses (0, 1 yr)

Indications

Ages 11-35, college students, asplenia, complement deficiency, microbiologists

Contraindications

Severe allergic reaction

Notes

MenB covers serogroup B (responsible for college outbreaks). Give separately from MenACWY.

Rotavirus

Schedule

3 doses (ages 2, 4, 6 months) or 2 doses for Rotarix

Indications

All infants

Contraindications

Intussusception history, SCID, severe allergic reaction

Notes

Oral vaccine. Must complete series before 8 months of age.

Polio (IPV)

Schedule

4 doses (2, 4, 6-18 months, 4-6 years)

Indications

All children, unvaccinated adults

Contraindications

Severe allergic reaction to neomycin/streptomycin

Notes

US uses inactivated vaccine (IPV). Booster for travelers to endemic areas.

Diphtheria, Pertussis, Tetanus (see Tdap)

Schedule

See Tdap above

Indications

See Tdap above

Contraindications

See Tdap above

Notes

Most adults receive Tdap as adult form; children receive DTaP series.

Haemophilus influenzae B (Hib)

Schedule

3 doses (2, 4, 6 months) + booster (12-15 months)

Indications

All children; adults with asplenia, complement deficiency

Contraindications

Severe allergic reaction

Notes

Major cause of meningitis in unvaccinated children.

Pneumococcal (Pneumococcus)

Schedule

PCV13 (children), PCV20 or PCV15+PPSV23 (adults ≥65 or risk factors)

Indications

All children <5, adults ≥65, chronic disease, asplenia, smoking

Contraindications

Severe allergic reaction

Notes

Covers 13-20 serotypes. PPSV23 for older vaccines/asplenic patients.

Measles, Mumps, Rubella (see MMR)

Schedule

See MMR above

Indications

See MMR above

Contraindications

See MMR above

Notes

Highly contagious. Immunity critical for healthcare workers and travelers.

Varicella (Chickenpox)

Schedule

See Varicella above

Indications

See Varicella above

Contraindications

See Varicella above

Notes

Can cause zoster (shingles) reactivation in immunocompromised.

Japanese Encephalitis (JE-VC)

Schedule

2 doses separated by 28 days

Indications

Travel to endemic areas (Asia), research workers

Contraindications

Severe allergic reaction, Guillain-Barré history

Notes

Consider if >1 month in endemic areas. Vero cell vaccine highly effective.

Yellow Fever

Schedule

Single dose (booster every 30 years if high-risk exposure)

Indications

Travel to endemic areas (Africa, South America)

Contraindications

Age <6 months, severe immunodeficiency, egg allergy

Notes

One of most effective vaccines (95% protection). Certificate required for travel to some countries.

Rabies

Schedule

3 doses pre-exposure (0, 7, 21-28 days); post-exposure varies by exposure type

Indications

High-risk occupations (veterinarians, zookeepers), animal exposure, travelers to high-risk areas

Contraindications

Severe allergic reaction

Notes

100% effective if given before symptom onset. Post-exposure prophylaxis = vaccine + rabies immunoglobulin.

Typhoid (Typhim Vi or Ty21a)

Schedule

1 dose (inactivated); 4 capsules (oral) every other day x 4

Indications

Travel to endemic areas, high-risk contacts

Contraindications

Severe allergic reaction, fever (oral vaccine)

Notes

Oral vaccine less effective. Parenteral typhoid combined with hepatitis A available (Vivaxim).

Cholera (Vaxchora)

Schedule

Single dose (1-2 weeks before travel)

Indications

Travel to endemic areas (rarely needed in developed countries)

Contraindications

Hypersensitivity to ingredients, significant GI disease

Notes

Oral vaccine. Protects ~90% against Vibrio cholerae for 3 years.

Pertussis (see Tdap)

Schedule

See Tdap above

Indications

See Tdap above

Contraindications

See Tdap above

Notes

In Tdap (acellular) form. Associated with fewer side effects than whole-cell vaccine.

Rotavirus (RV5 or RV1)

Schedule

2-3 doses depending on brand

Indications

All infants (critical in first 6 months of life)

Contraindications

Intussusception history, SCID

Notes

Oral vaccine. Provides excellent protection (>90%) against severe gastroenteritis.

Lyme Disease (LYMErix)

Schedule

Not currently available (withdrawn from market)

Indications

Was for endemic areas (Northeast US, Wisconsin, Minnesota)

Contraindications

N/A

Notes

Vaccine withdrawn in 2002 due to public concerns, though safety was supported by evidence.

Smallpox/Monkeypox (JYNNEOS)

Schedule

2 doses separated by 2-4 weeks (subcutaneous)

Indications

Orthopoxvirus exposure, high-risk contacts, travelers to endemic areas

Contraindications

Severe immunodeficiency, severe allergic reaction

Notes

Newer vaccine for monkeypox with fewer side effects than older vaccines.

RSV (Arexvy/Abrysvo)

Schedule

Single dose (newly approved for adults ≥60)

Indications

Adults ≥60, especially those at risk for severe RSV disease

Contraindications

Severe allergic reaction

Notes

New vaccine approved 2023. Reduces RSV LRTI by 70-80% in older adults.

Mpox (Monkeypox/JYNNEOS)

Schedule

See Smallpox/Monkeypox above

Indications

See Smallpox/Monkeypox above

Contraindications

See Smallpox/Monkeypox above

Notes

Same vaccine as smallpox. Originally developed for smallpox, provides cross-protection.

Created by Safana Abdullah

For educational purposes only. Always consult a medical professional for diagnosis and treatment.

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